DS-6051b is an orally administered inhibitor of the tyrosine kinases ROS1 and NTRKs. This phase 1 first-in-human study evaluates safety and tolerability of DS-6051b in cancer subjects and identify a recommended phase 2 dose (RP2D). In addition, this study will also assess the pharmacokinetic (PK)/pharmacodynamic (PD) profiles and preliminary efficacy… Read more »